Chemicals and Drugs

Corticosterone

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

Chemical Identity

Chemical Information

Molecular Formula
C21H30O4
Molecular Weight
346.5 g/mol
CAS Registry No.
50-22-6
IUPAC Name
(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKey
OMFXVFTZEKFJBZ-HJTSIMOOSA-N
SMILES
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O
MeSH Unique ID
D003345
Source
PubChem CID 5753

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.745w.654w.237w
  2. D06.472w.040.585w.353.237w

MeSH Record

NLM Classification

WK 755

AMA Style

References

  1. National Library of Medicine. Corticosterone. Medical Subject Headings (MeSH). 2026. Unique ID D003345. http://id.nlm.nih.gov/mesh/2026/D003345
  2. Corticosterone. In: Wikipedia. https://en.wikipedia.org/wiki/Corticosterone
  3. Corticosterone. In: Wikidata. https://www.wikidata.org/wiki/Q422543
  4. Corticosterone. In: PubChem Compound. CID 5753. https://pubchem.ncbi.nlm.nih.gov/compound/5753