Structured Summary
Abstract
17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.
Chemical Identity
Chemical Information
- Molecular Formula
- C21H30O4
- Molecular Weight
- 346.5 g/mol
- CAS Registry No.
- 152-58-9
- IUPAC Name
- (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
- InChIKey
- WHBHBVVOGNECLV-OBQKJFGGSA-N
- SMILES
- C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C
- MeSH Unique ID
- D003350
- Source
- PubChem CID 440707
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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MeSH Record
Synonyms
11 entry terms
- 11-Deoxycortisol
- 11-Desoxycortisol
- 11-Desoxycortisone
- Cortexolone
- Reichstein's Substance S
- 11 Deoxycortisol
- 11 Desoxycortisol
- 11 Desoxycortisone
- Reichstein Substance S
- Reichsteins Substance S
- Substance S, Reichstein's
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
an anti-inflamm agent
MeSH Record
History Note
91(75); was see under 17-HYDROXYCORTICOSTEROIDS 1975-90
MeSH Record
Previous Indexing
- 17-Hydroxycorticosteroids (1974)
- Pregnenediones (1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Cortodoxone. Medical Subject Headings (MeSH). 2026. Unique ID D003350. http://id.nlm.nih.gov/mesh/2026/D003350
- Cortodoxone. In: Wikipedia. https://en.wikipedia.org/wiki/11-Deoxycortisol
- Cortodoxone. In: Wikidata. https://www.wikidata.org/wiki/Q2064915
- Cortodoxone. In: PubChem Compound. CID 440707. https://pubchem.ncbi.nlm.nih.gov/compound/440707