Chemicals and Drugs

Creatine Kinase

A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.

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MeSH Record

Synonyms

11 entry terms
  • ADP Phosphocreatine Phosphotransferase
  • ATP Creatine Phosphotransferase
  • Creatine Phosphokinase
  • Creatine Phosphotransferase, ATP
  • Kinase, Creatine
  • Phosphocreatine Phosphotransferase, ADP
  • Phosphokinase, Creatine
  • Phosphotransferase, ADP Phosphocreatine
  • Phosphotransferase, ATP Creatine
  • Macro-Creatine Kinase
  • Macro Creatine Kinase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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QU 141

AMA Style

References

  1. National Library of Medicine. Creatine Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D003402. http://id.nlm.nih.gov/mesh/2026/D003402
  2. Creatine Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Creatine_kinase
  3. Creatine Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q409458