Chemicals and Drugs

Cross-Linking Reagents

Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

15 entry terms
  • Bifunctional Reagent
  • Bifunctional Reagents
  • Cross Linking Reagent
  • Cross Linking Reagents
  • Crosslinking Reagent
  • Crosslinking Reagents
  • Linking Reagent, Cross
  • Linking Reagents, Cross
  • Reagent, Bifunctional
  • Reagent, Cross Linking
  • Reagent, Crosslinking
  • Reagents, Bifunctional
  • Reagents, Cross Linking
  • Reagents, Cross-Linking
  • Reagents, Crosslinking

MeSH Record

Aspects Covered

18 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

History Note

80

MeSH Record

Previous Indexing

  • Indicators and Reagents (1966-1979)
  • Protein Binding (1966-1979)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Cross-Linking Reagents. Medical Subject Headings (MeSH). 2026. Unique ID D003432. http://id.nlm.nih.gov/mesh/2026/D003432
  2. Cross-Linking Reagents. In: Wikidata. https://www.wikidata.org/wiki/Q50429956