Chemicals and Drugs

Cyclin-Dependent Kinase 8

A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is activated by its interaction with CYCLIN C and plays a role in transcriptional regulation by phosphorylating RNA POLYMERASE II.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is activated by its interaction with CYCLIN C and plays a role in transcriptional regulation by phosphorylating RNA POLYMERASE II.

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Classification

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MeSH Record

Synonyms

9 entry terms
  • Cdk8 Cyclin-Dependent Kinase
  • Cdk8 Protein Kinase
  • Cell Division Protein Kinase 8
  • Cdk8 Cyclin Dependent Kinase
  • Cyclin Dependent Kinase 8
  • Cyclin-Dependent Kinase, Cdk8
  • Kinase, Cdk8 Cyclin-Dependent
  • Kinase, Cdk8 Protein
  • Protein Kinase, Cdk8

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010

MeSH Record

Previous Indexing

  • Cyclin-Dependent Kinases (1995-2009)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cyclin-Dependent Kinase 8. Medical Subject Headings (MeSH). 2026. Unique ID D056850. http://id.nlm.nih.gov/mesh/2026/D056850
  2. Cyclin-Dependent Kinase 8. In: Wikidata. https://www.wikidata.org/wiki/Q5198254