Chemicals and Drugs

Cycloheximide

Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.

Chemical Identity

Chemical Information

Molecular Formula
C15H23NO4
Molecular Weight
281.35 g/mol
CAS Registry No.
66-81-9
IUPAC Name
4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
InChIKey
YPHMISFOHDHNIV-FSZOTQKASA-N
SMILES
C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C
MeSH Unique ID
D003513
Source
PubChem CID 6197

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Cicloheximide
  • Actidione

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

68(66)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Cycloheximide. Medical Subject Headings (MeSH). 2026. Unique ID D003513. http://id.nlm.nih.gov/mesh/2026/D003513
  2. Cycloheximide. In: Wikipedia. https://en.wikipedia.org/wiki/Cycloheximide
  3. Cycloheximide. In: Wikidata. https://www.wikidata.org/wiki/Q412895
  4. Cycloheximide. In: PubChem Compound. CID 6197. https://pubchem.ncbi.nlm.nih.gov/compound/6197