Chemicals and Drugs

Cyproterone

An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.

Chemical Identity

Chemical Information

Molecular Formula
C22H27ClO3
Molecular Weight
374.9 g/mol
CAS Registry No.
2098-66-0
IUPAC Name
(1S,2S,3S,5R,11R,12S,15R,16S)-15-acetyl-9-chloro-15-hydroxy-2,16-dimethylpentacyclo[9.7.0.02,8.03,5.012,16]octadeca-7,9-dien-6-one
InChIKey
DUSHUSLJJMDGTE-ZJPMUUANSA-N
SMILES
CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)[C@@H]5C[C@@H]5[C@]34C)Cl)C)O
MeSH Unique ID
D003534
Source
PubChem CID 5284537

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Cyproterone, 1alpha,2 alpha,9 beta,10 alpha-Isomer

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

74(72)

MeSH Record

Previous Indexing

  • Androgens/antagonists & inhibitors (1968-1971)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.432w.219w
  2. D04w.210.500w.883.419w

MeSH Record

NLM Classification

WJ 875

AMA Style

References

  1. National Library of Medicine. Cyproterone. Medical Subject Headings (MeSH). 2026. Unique ID D003534. http://id.nlm.nih.gov/mesh/2026/D003534
  2. Cyproterone. In: Wikipedia. https://en.wikipedia.org/wiki/Cyproterone
  3. Cyproterone. In: Wikidata. https://www.wikidata.org/wiki/Q7381206
  4. Cyproterone. In: PubChem Compound. CID 5284537. https://pubchem.ncbi.nlm.nih.gov/compound/5284537