Chemicals and Drugs

Cystatins

A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

18 entry terms
  • Cystatin
  • Cystatin Superfamily
  • Cystatin-Related Proteins
  • Stefin
  • Stefins
  • Type 1 Cystatins
  • Type 2 Cystatins
  • Type 3 Cystatins
  • Type I Cystatins
  • Type II Cystatins
  • Type III Cystatins
  • Cystatin Related Proteins
  • Cystatins, Type 1
  • Cystatins, Type 2
  • Cystatins, Type 3
  • Cystatins, Type I
  • Cystatins, Type II
  • Cystatins, Type III

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Enzyme Inhibitors (1975-1978)
  • Protease Inhibitors (1979-1989)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Cystatins. Medical Subject Headings (MeSH). 2026. Unique ID D015891. http://id.nlm.nih.gov/mesh/2026/D015891
  2. Cystatins. In: Wikipedia. https://en.wikipedia.org/wiki/Cystatin
  3. Cystatins. In: Wikidata. https://www.wikidata.org/wiki/Q4505907