Structured Summary
Abstract
An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
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Classification
Broader headings
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MeSH Record
Synonyms
9 entry terms
- DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein
- NR0B1 Protein
- Nuclear Receptor 0B1
- Nuclear Receptor DAX-1
- Nuclear Receptor NR0B1
- Nuclear Receptor Subfamily 0, Group B, Member 1
- DAX 1 Orphan Nuclear Receptor
- DSS AHC Critical Region on the X Chromosome, Gene 1 Protein
- Nuclear Receptor DAX 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2010(1995)
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AMA Style
References
- National Library of Medicine. DAX-1 Orphan Nuclear Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D057137. http://id.nlm.nih.gov/mesh/2026/D057137
- DAX-1 Orphan Nuclear Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q5204362