Phenomena and Processes

DNA Cleavage

A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone of DNA. It is catalyzed enzymatically, chemically or by radiation. Cleavage may be exonucleolytic - removing the end nucleotide, or endonucleolytic - splitting the strand in two.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone of DNA. It is catalyzed enzymatically, chemically or by radiation. Cleavage may be exonucleolytic - removing the end nucleotide, or endonucleolytic - splitting the strand in two.

MeSH Record

Classification

Broader headings

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MeSH Record

Aspects Covered

2 allowable subheadings

Indexed with the subheadings drug effects, radiation effects.

MeSH Record

History Note

2007

MeSH Hierarchy

Tree Numbers

  1. G02.111.210
  2. G05.193

AMA Style

References

  1. National Library of Medicine. DNA Cleavage. Medical Subject Headings (MeSH). 2026. Unique ID D053837. http://id.nlm.nih.gov/mesh/2026/D053837
  2. DNA Cleavage. In: Wikidata. https://www.wikidata.org/wiki/Q64699191