Structured Summary
Abstract
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
8 entry terms
- DNA Glycosylase
- DNA N-glycosidase
- DNA N glycosidase
- Glycosylase, DNA
- Glycosylases, DNA
- Methylpurine DNA Glycosylase
- DNA Glycosylase, Methylpurine
- Glycosylase, Methylpurine DNA
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2004; use DNA GLYCOSIDASES (NM) 1980-2003
MeSH Record
Previous Indexing
- DNA (1978-1981)
- Glycoside Hydrolases (1978-1981)
- N-Glycosyl Hydrolases (1982-2003)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. DNA Glycosylases. Medical Subject Headings (MeSH). 2026. Unique ID D045647. http://id.nlm.nih.gov/mesh/2026/D045647
- DNA Glycosylases. In: Wikipedia. https://en.wikipedia.org/wiki/DNA_glycosylase
- DNA Glycosylases. In: Wikidata. https://www.wikidata.org/wiki/Q413156