Organisms

Defective Interfering Viruses

Naturally occurring or synthetically made defective mutant viral genomes and particles which are incompetent in independent replication and interfere with normal VIRUS REPLICATION. Some synthetic defective interfering genomes may stimulate INNATE IMMUNE RESPONSE and are candidates for potential vaccine and therapeutic approaches for virus infections.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Naturally occurring or synthetically made defective mutant viral genomes and particles which are incompetent in independent replication and interfere with normal VIRUS REPLICATION. Some synthetic defective interfering genomes may stimulate INNATE IMMUNE RESPONSE and are candidates for potential vaccine and therapeutic approaches for virus infections.

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Classification

Broader headings

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MeSH Record

Synonyms

16 entry terms
  • Defective Interfering Particles
  • Defective Interfering Particle
  • Defective Interfering Virus
  • Interfering Particle, Defective
  • Interfering Virus, Defective
  • Particle, Defective Interfering
  • Virus, Defective Interfering
  • Defective Interfering Genome
  • Natural Defective Interfering Viruses
  • Synthetic Defective Interfering Genome Viruses
  • Synthetic Defective Interfering Particles
  • Synthetic Defective Interfering Virus
  • Synthetic Defective Interfering Viruses
  • Defective Interfering Genomes
  • Genome, Defective Interfering
  • Interfering Genome, Defective

MeSH Record

Aspects Covered

13 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, growth & development, immunology, isolation & purification, metabolism, pathogenicity, physiology, radiation effects, ultrastructure.

MeSH Record

History Note

2022(1988)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Defective Interfering Viruses. Medical Subject Headings (MeSH). 2026. Unique ID D000089783. http://id.nlm.nih.gov/mesh/2026/D000089783
  2. Defective Interfering Viruses. In: Wikipedia. https://en.wikipedia.org/wiki/Defective_interfering_particle
  3. Defective Interfering Viruses. In: Wikidata. https://www.wikidata.org/wiki/Q5251124