Chemicals and Drugs

Degenerin Sodium Channels

A family of mechanosensitive sodium channels found primarily in NEMATODES where they play a role in CELLULAR MECHANOTRANSDUCTION. Degenerin sodium channels are structurally-related to EPITHELIAL SODIUM CHANNELS and are named after the fact that loss of their activity results in cellular degeneration.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of mechanosensitive sodium channels found primarily in NEMATODES where they play a role in CELLULAR MECHANOTRANSDUCTION. Degenerin sodium channels are structurally-related to EPITHELIAL SODIUM CHANNELS and are named after the fact that loss of their activity results in cellular degeneration.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • Degenerin
  • Degenerin Ion Channels
  • Degenerin Sodium Ion Channels
  • Degenerins
  • Ion Channels, Degenerin
  • Sodium Channels, Degenerin

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013

MeSH Record

Previous Indexing

  • Epithelial Sodium Channels (2007-2012)
  • Ion Channels (1996-2006)
  • Nerve Tissue Proteins (2007-2012)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.875w.100
  2. D12.776w.543w.550w.450w.875w.100
  3. D12.776w.543w.585w.400w.875w.100

AMA Style

References

  1. National Library of Medicine. Degenerin Sodium Channels. Medical Subject Headings (MeSH). 2026. Unique ID D062626. http://id.nlm.nih.gov/mesh/2026/D062626
  2. Degenerin Sodium Channels. In: Wikidata. https://www.wikidata.org/wiki/Q24784635