Structured Summary
Abstract
A derivative of benzodiazepine that acts on the cholecystokinin A (CCKA) receptor to antagonize CCK-8's (SINCALIDE) physiological and behavioral effects, such as pancreatic stimulation and inhibition of feeding.
Chemical Identity
Chemical Information
- Molecular Formula
- C25H20N4O2
- Molecular Weight
- 408.5 g/mol
- CAS Registry No.
- 103420-77-5
- IUPAC Name
- N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
- InChIKey
- NFHRQQKPEBFUJK-HSZRJFAPSA-N
- SMILES
- CN1C2=CC=CC=C2C(=N[C@@H](C1=O)NC(=O)C3=CC4=CC=CC=C4N3)C5=CC=CC=C5
- MeSH Unique ID
- D020109
- Source
- PubChem CID 443375
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- L-364,718
- MK-329
- L 364,718
- L364,718
- MK 329
- MK329
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
1999; use DEVAZEPIDE (NM) 1986-1998
MeSH Record
Previous Indexing
- Benzodiazepinones (1986-1998)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Devazepide. Medical Subject Headings (MeSH). 2026. Unique ID D020109. http://id.nlm.nih.gov/mesh/2026/D020109
- Devazepide. In: Wikipedia. https://en.wikipedia.org/wiki/Devazepide
- Devazepide. In: Wikidata. https://www.wikidata.org/wiki/Q5266620
- Devazepide. In: PubChem Compound. CID 443375. https://pubchem.ncbi.nlm.nih.gov/compound/443375