Chemicals and Drugs

Dextran Sulfate

Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

6 entry terms
  • Sulfate, Dextran
  • Dextran Sulfate Sodium
  • Sodium Dextran Sulfate
  • Dextran Sulfate, Sodium
  • Sulfate Sodium, Dextran
  • Sulfate, Sodium Dextran

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • Dextrans (1966-1990)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Dextran Sulfate. Medical Subject Headings (MeSH). 2026. Unique ID D016264. http://id.nlm.nih.gov/mesh/2026/D016264
  2. Dextran Sulfate. In: Wikidata. https://www.wikidata.org/wiki/Q50350128