Chemicals and Drugs

Diazepam Binding Inhibitor

An 86-amino acid polypeptide, found in central and peripheral tissues, that displaces diazepam from the benzodiazepine recognition site on the gamma-aminobutyric acid receptor (RECEPTORS, GABA). It also binds medium- and long-chain acyl-CoA esters and serves as an acyl-CoA transporter. This peptide regulates lipid metabolism.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An 86-amino acid polypeptide, found in central and peripheral tissues, that displaces diazepam from the benzodiazepine recognition site on the gamma-aminobutyric acid receptor (RECEPTORS, GABA). It also binds medium- and long-chain acyl-CoA esters and serves as an acyl-CoA transporter. This peptide regulates lipid metabolism.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

11 entry terms
  • Acyl-CoA-Binding Protein
  • DBI Peptide
  • Endozepine
  • EpDBI
  • Acyl CoA Binding Protein
  • Binding Inhibitor, Diazepam
  • Inhibitor, Diazepam Binding
  • Peptide, DBI
  • Protein, Acyl-CoA-Binding
  • Medium-Chain Acyl CoA-Binding Protein
  • Medium Chain Acyl CoA Binding Protein

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2002; use DIAZEPAM BINDING INHIBITOR (NM) 1984-2001

MeSH Record

Previous Indexing

  • Carrier Proteins (1992-2001)
  • Nerve Tissue Proteins (1984-1986)
  • Neuropeptides (1987-1992)

MeSH Hierarchy

Tree Number

  1. D12.644w.136

AMA Style

References

  1. National Library of Medicine. Diazepam Binding Inhibitor. Medical Subject Headings (MeSH). 2026. Unique ID D026261. http://id.nlm.nih.gov/mesh/2026/D026261
  2. Diazepam Binding Inhibitor. In: Wikidata. https://www.wikidata.org/wiki/Q22676699