Chemicals and Drugs

Dihydroorotase

An enzyme that, in the course of pyrimidine biosynthesis, catalyzes ring closure by removal of water from N-carbamoylaspartate to yield dihydro-orotic acid. EC 3.5.2.3.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that, in the course of pyrimidine biosynthesis, catalyzes ring closure by removal of water from N-carbamoylaspartate to yield dihydro-orotic acid. EC 3.5.2.3.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

7 entry terms
  • Carbamoylaspartic Dehydrase
  • Dihydro-Orotase
  • Dihydro-Orotate Amidohydrolase
  • Amidohydrolase, Dihydro-Orotate
  • Dehydrase, Carbamoylaspartic
  • Dihydro Orotase
  • Dihydro Orotate Amidohydrolase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

95; was DIHYDRO-OROTASE 1977-94 (see under AMIDOHYDROLASES 1977-90)

MeSH Record

Previous Indexing

  • Amidohydrolases (1966-1976)
  • Orotic Acid (1966-1976)

MeSH Hierarchy

Tree Number

  1. D08.811w.277w.087w.280w

AMA Style

References

  1. National Library of Medicine. Dihydroorotase. Medical Subject Headings (MeSH). 2026. Unique ID D004080. http://id.nlm.nih.gov/mesh/2026/D004080
  2. Dihydroorotase. In: Wikipedia. https://en.wikipedia.org/wiki/Dihydroorotase
  3. Dihydroorotase. In: Wikidata. https://www.wikidata.org/wiki/Q5276440