Chemicals and Drugs

Dihydropteridine Reductase

An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.

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Classification

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See Also

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Synonyms

4 entry terms
  • 6,7-Dihydropteridine Reductase
  • 6,7 Dihydropteridine Reductase
  • Reductase, 6,7-Dihydropteridine
  • Reductase, Dihydropteridine

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(75); was see under NADH, NADPH OXIDOREDUCTASES 1975-90

MeSH Record

Previous Indexing

  • NADH, NADPH Oxidoreductases (1973-1974)
  • Pteridines (1973-1974)

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AMA Style

References

  1. National Library of Medicine. Dihydropteridine Reductase. Medical Subject Headings (MeSH). 2026. Unique ID D004093. http://id.nlm.nih.gov/mesh/2026/D004093
  2. Dihydropteridine Reductase. In: Wikipedia. https://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase
  3. Dihydropteridine Reductase. In: Wikidata. https://www.wikidata.org/wiki/Q1153224