Chemicals and Drugs

Dihydrotestosterone

A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.

Chemical Identity

Chemical Information

Molecular Formula
C19H30O2
Molecular Weight
290.4 g/mol
CAS Registry No.
521-18-6
IUPAC Name
(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
InChIKey
NVKAWKQGWWIWPM-ABEVXSGRSA-N
SMILES
C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C
MeSH Unique ID
D013196
Source
PubChem CID 10635

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

19 entry terms
  • 17beta-Hydroxy-5alpha-Androstan-3-One
  • 5 alpha-Dihydrotestosterone
  • 5-alpha Dihydrotestosterone
  • 5-alpha-DHT
  • Androstanolone
  • Stanolone
  • 17beta Hydroxy 5alpha Androstan 3 One
  • 5 alpha DHT
  • 5 alpha Dihydrotestosterone
  • Dihydrotestosterone, 5-alpha
  • 17 beta-Hydroxy-5 beta-Androstan-3-One
  • 5 beta-Dihydrotestosterone
  • Anaprotin
  • Andractim
  • Dihydroepitestosterone
  • Gelovit
  • 17 beta Hydroxy 5 beta Androstan 3 One
  • 5 beta Dihydrotestosterone
  • beta-Hydroxy-5 beta-Androstan-3-One, 17

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2004 (1963)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.054.040w.248w
  2. D06.472w.334.851w.968.964w

AMA Style

References

  1. National Library of Medicine. Dihydrotestosterone. Medical Subject Headings (MeSH). 2026. Unique ID D013196. http://id.nlm.nih.gov/mesh/2026/D013196
  2. Dihydrotestosterone. In: Wikipedia. https://en.wikipedia.org/wiki/Dihydrotestosterone
  3. Dihydrotestosterone. In: Wikidata. https://www.wikidata.org/wiki/Q411054
  4. Dihydrotestosterone. In: PubChem Compound. CID 10635. https://pubchem.ncbi.nlm.nih.gov/compound/10635