Structured Summary
Abstract
An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.
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Classification
Broader headings
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Synonyms
8 entry terms
- Dimethylallyltransferase
- Dolichyl Phosphate Synthetase
- Geranylpyrophosphate Synthetase
- Nerylpyrophosphate Synthetase
- Prenyltransferase
- Synthetase, Geranylpyrophosphate
- Synthetase, Nerylpyrophosphate
- Geranylgeranyl Pyrophosphate Synthetase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90)
MeSH Record
Previous Indexing
- Allyl Compounds (1971-1978)
- Transferases (1966-1978)
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AMA Style
References
- National Library of Medicine. Dimethylallyltranstransferase. Medical Subject Headings (MeSH). 2026. Unique ID D004122. http://id.nlm.nih.gov/mesh/2026/D004122
- Dimethylallyltranstransferase. In: Wikipedia. https://en.wikipedia.org/wiki/Dimethylallyltranstransferase
- Dimethylallyltranstransferase. In: Wikidata. https://www.wikidata.org/wiki/Q21107439