Chemicals and Drugs

Dinitrochlorobenzene

A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds.

Chemical Identity

Chemical Information

Molecular Formula
C6H3ClN2O4
Molecular Weight
202.55 g/mol
CAS Registry No.
97-00-7
IUPAC Name
1-chloro-2,4-dinitrobenzene
InChIKey
VYZAHLCBVHPDDF-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])Cl
MeSH Unique ID
D004137
Source
PubChem CID 6

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Chlorodinitrobenzene
  • DNCB
  • 1-Chloro-2,4-Dinitrobenzene
  • 2,4-Dinitrochlorobenzene
  • Benzene, 1-Chloro-2,4-Dinitro-
  • 1 Chloro 2,4 Dinitrobenzene
  • 2,4 Dinitrochlorobenzene

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87(75); was see under NITROBENZENES 1975-86

MeSH Record

Previous Indexing

  • Chlorine (1971-1974)
  • Nitrobenzenes (1971-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.389.261.250w
  2. D02w.455w.426w.559w.389.565w.250w
  3. D02w.455w.526.439.202.200w
  4. D02w.640w.529w.240w.250w
  5. D23.050w.550w.480w.350w

AMA Style

References

  1. National Library of Medicine. Dinitrochlorobenzene. Medical Subject Headings (MeSH). 2026. Unique ID D004137. http://id.nlm.nih.gov/mesh/2026/D004137
  2. Dinitrochlorobenzene. In: Wikipedia. https://en.wikipedia.org/wiki/2,4-Dinitrochlorobenzene
  3. Dinitrochlorobenzene. In: Wikidata. https://www.wikidata.org/wiki/Q209216
  4. Dinitrochlorobenzene. In: PubChem Compound. CID 6. https://pubchem.ncbi.nlm.nih.gov/compound/6