Chemicals and Drugs

Diosgenin

A spirostan found in DIOSCOREA and other plants. The 25S isomer is called yamogenin. Solasodine is a natural derivative formed by replacing the spiro-ring with a nitrogen, which can rearrange to SOLANINE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A spirostan found in DIOSCOREA and other plants. The 25S isomer is called yamogenin. Solasodine is a natural derivative formed by replacing the spiro-ring with a nitrogen, which can rearrange to SOLANINE.

Chemical Identity

Chemical Information

Molecular Formula
C27H42O3
Molecular Weight
414.6 g/mol
CAS Registry No.
512-04-9
IUPAC Name
(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol
InChIKey
WQLVFSAGQJTQCK-VKROHFNGSA-N
SMILES
C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1
MeSH Unique ID
D004144
Source
PubChem CID 99474

MeSH Record

Classification

Broader headings

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MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(79); was see under SAPOGENINS 1979-90

MeSH Record

Previous Indexing

  • Hydroxysteroids (1972-1975)
  • Saponins (1966-1975)
  • Spirostans (1968-1978)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QU 95

AMA Style

References

  1. National Library of Medicine. Diosgenin. Medical Subject Headings (MeSH). 2026. Unique ID D004144. http://id.nlm.nih.gov/mesh/2026/D004144
  2. Diosgenin. In: Wikipedia. https://en.wikipedia.org/wiki/Diosgenin
  3. Diosgenin. In: Wikidata. https://www.wikidata.org/wiki/Q1107734
  4. Diosgenin. In: PubChem Compound. CID 99474. https://pubchem.ncbi.nlm.nih.gov/compound/99474