Chemicals and Drugs

Diphosphonates

Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Bisphosphonate
  • Bisphosphonates

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

77

MeSH Record

Previous Indexing

  • Organophosphorus Compounds (1971-1976)
  • Phosphonic Acids (1966-1976)

MeSH Hierarchy

Tree Number

  1. D02w.705w.429.500w

AMA Style

References

  1. National Library of Medicine. Diphosphonates. Medical Subject Headings (MeSH). 2026. Unique ID D004164. http://id.nlm.nih.gov/mesh/2026/D004164
  2. Diphosphonates. In: Wikipedia. https://en.wikipedia.org/wiki/Bisphosphonate
  3. Diphosphonates. In: Wikidata. https://www.wikidata.org/wiki/Q412205