Chemicals and Drugs

Diprenorphine

A narcotic antagonist similar in action to NALOXONE. It is used to remobilize animals after ETORPHINE neuroleptanalgesia and is considered a specific antagonist to etorphine.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A narcotic antagonist similar in action to NALOXONE. It is used to remobilize animals after ETORPHINE neuroleptanalgesia and is considered a specific antagonist to etorphine.

Chemical Identity

Chemical Information

Molecular Formula
C26H35NO4
Molecular Weight
425.6 g/mol
CAS Registry No.
14357-78-9
IUPAC Name
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-(2-hydroxypropan-2-yl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
InChIKey
OIJXLIIMXHRJJH-KNLIIKEYSA-N
SMILES
CC(C)([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O
MeSH Unique ID
D004174
Source
PubChem CID 443408

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Diprenorphine Hydrochloride
  • Revivon
  • Hydrochloride, Diprenorphine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(76); was see under MORPHINANS 1976-90

MeSH Record

Previous Indexing

  • Cyclopropanes (1973-1975)
  • Morphinans (1973-1975)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.577.249.250w
  2. D03w.605.497.280w
  3. D03w.633.400.686.275w
  4. D04w.615w.723w.795.250w

AMA Style

References

  1. National Library of Medicine. Diprenorphine. Medical Subject Headings (MeSH). 2026. Unique ID D004174. http://id.nlm.nih.gov/mesh/2026/D004174
  2. Diprenorphine. In: Wikipedia. https://en.wikipedia.org/wiki/Diprenorphine
  3. Diprenorphine. In: Wikidata. https://www.wikidata.org/wiki/Q424009
  4. Diprenorphine. In: PubChem Compound. CID 443408. https://pubchem.ncbi.nlm.nih.gov/compound/443408