Chemicals and Drugs

Dithioerythritol

A compound that, along with its isomer, Cleland's reagent (DITHIOTHREITOL), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl groups.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A compound that, along with its isomer, Cleland's reagent (DITHIOTHREITOL), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl groups.

Chemical Identity

Chemical Information

Molecular Formula
C4H10O2S2
Molecular Weight
154.3 g/mol
CAS Registry No.
6892-68-8
IUPAC Name
(2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol
InChIKey
VHJLVAABSRFDPM-ZXZARUISSA-N
SMILES
C([C@H]([C@H](CS)O)O)S
MeSH Unique ID
D004226
Source
PubChem CID 439352

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Dithioerythreitol
  • 2,3-Dihydroxy-1,4-dithiolbutane

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under DITHIOTHREITOL 1975-90

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Dithioerythritol. Medical Subject Headings (MeSH). 2026. Unique ID D004226. http://id.nlm.nih.gov/mesh/2026/D004226
  2. Dithioerythritol. In: Wikipedia. https://en.wikipedia.org/wiki/Dithioerythritol
  3. Dithioerythritol. In: Wikidata. https://www.wikidata.org/wiki/Q412701
  4. Dithioerythritol. In: PubChem Compound. CID 439352. https://pubchem.ncbi.nlm.nih.gov/compound/439352