Chemicals and Drugs

Dolichols

A class of polyprenols which contain approximately 20 isoprene residues. Although considered ISOPRENOIDS, they terminate with an alpha-saturated isoprenoid group at the hydroxy end of the molecule.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of polyprenols which contain approximately 20 isoprene residues. Although considered ISOPRENOIDS, they terminate with an alpha-saturated isoprenoid group at the hydroxy end of the molecule.

Chemical Identity

Chemical Information

Molecular Formula
C100H164O
Molecular Weight
1382.4 g/mol
IUPAC Name
(6E,10E,14E,18E,22Z,26E,30E,34E,38E,42E,46E,50E,54E,58Z,62E,66E,70E,74E)-3,7,11,15,19,23,27,31,35,39,43,47,51,55,59,63,67,71,75,79-icosamethyloctaconta-6,10,14,18,22,26,30,34,38,42,46,50,54,58,62,66,70,74,78-nonadecaen-1-ol
InChIKey
KEVPZUBEAUSPNJ-OYHKHEHLSA-N
SMILES
CC(CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)CCO
MeSH Unique ID
D004286
Source
PubChem CID 6433320

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

5 entry terms
  • 6,10,14,18,22,26,30,34,38,42,46,50,54,58,62,66,70,74,78-Octacontanonadecaen-1-ol, 3,7,11,15,19,23,27,31,35,39,43,47,51,55,59,63,67,71,75,79-eicosamethyl-
  • Dolichol
  • Eicosamethyl Octacontanonadecasen-1-ol
  • Eicosamethyl Octacontanonadecasen 1 ol
  • Octacontanonadecasen-1-ol, Eicosamethyl

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2020(1975)

MeSH Record

Previous Indexing

  • Diterpenes (1974)
  • Fatty Alcohols (1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.318w
  2. D02w.033w.415w.230w
  3. D02w.455w.849w.366w
  4. D10w.289w.230w

AMA Style

References

  1. National Library of Medicine. Dolichols. Medical Subject Headings (MeSH). 2026. Unique ID D004286. http://id.nlm.nih.gov/mesh/2026/D004286
  2. Dolichols. In: Wikipedia. https://en.wikipedia.org/wiki/Dolichol
  3. Dolichols. In: Wikidata. https://www.wikidata.org/wiki/Q418203
  4. Dolichols. In: PubChem Compound. CID 6433320. https://pubchem.ncbi.nlm.nih.gov/compound/6433320