Chemicals and Drugs

Dronabinol

A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.

Chemical Identity

Chemical Information

Molecular Formula
C21H30O2
Molecular Weight
314.5 g/mol
CAS Registry No.
1972-08-3
IUPAC Name
(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
InChIKey
CYQFCXCEBYINGO-IAGOWNOFSA-N
SMILES
CCCCCC1=CC(=C2[C@@H]3C=C(CC[C@H]3C(OC2=C1)(C)C)C)O
MeSH Unique ID
D013759
Source
PubChem CID 16078

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • 9-ene-Tetrahydrocannabinol
  • THC
  • Tetrahydrocannabinol
  • delta(1)-THC
  • delta(1)-Tetrahydrocannabinol
  • delta(9)-THC
  • delta(9)-Tetrahydrocannabinol
  • 9 ene Tetrahydrocannabinol
  • Marinol
  • Tetrahydrocannabinol, (6a-trans)-Isomer
  • Tetrahydrocannabinol, (6aR-cis)-Isomer
  • Tetrahydrocannabinol, (6aS-cis)-Isomer
  • Tetrahydrocannabinol, Trans-(+-)-Isomer
  • Tetrahydrocannabinol, Trans-Isomer
  • Tetrahydrocannabinol, Trans Isomer

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2014(1971);

MeSH Record

Previous Indexing

  • Cannabis (1966-1970)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 77.7

AMA Style

References

  1. National Library of Medicine. Dronabinol. Medical Subject Headings (MeSH). 2026. Unique ID D013759. http://id.nlm.nih.gov/mesh/2026/D013759
  2. Dronabinol. In: Wikipedia. https://en.wikipedia.org/wiki/Tetrahydrocannabinol
  3. Dronabinol. In: Wikidata. https://www.wikidata.org/wiki/Q190067
  4. Dronabinol. In: PubChem Compound. CID 16078. https://pubchem.ncbi.nlm.nih.gov/compound/16078