Diseases

Dysgerminoma

A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • Disgerminoma
  • Disgerminomas
  • Dysgerminomas

MeSH Record

Aspects Covered

39 allowable subheadings

Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, secondary, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

Indexing Annotation

coordinate with probably OVARIAN NEOPLASMS

MeSH Record

History Note

79; was DISGERMINOMA 1963-78

MeSH Hierarchy

Tree Number

  1. C04w.557.465.330w.300w

MeSH Record

NLM Classification

WP 322

AMA Style

References

  1. National Library of Medicine. Dysgerminoma. Medical Subject Headings (MeSH). 2026. Unique ID D004407. http://id.nlm.nih.gov/mesh/2026/D004407
  2. Dysgerminoma. In: Wikipedia. https://en.wikipedia.org/wiki/Dysgerminoma
  3. Dysgerminoma. In: Wikidata. https://www.wikidata.org/wiki/Q1269251