Structured Summary
Abstract
A plakin characterized by repeat sequences homologous to SPECTRIN and PLECTIN and C-terminal EF HAND MOTIFS. It functions as an integrator of INTERMEDIATE FILAMENTS, ACTIN and MICROTUBULES in cytoskeleton networks. It is required for anchoring intermediate filaments to the actin cytoskeleton in neural and muscle cells as well as anchoring KERATIN-containing intermediate filaments to HEMIDESMOSOMES in EPITHELIAL CELLS.
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Classification
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Synonyms
5 entry terms
- 230 kDa Bullous Pemphigoid Antigen
- 230-240 kDa Bullous Pemphigoid Antigen
- Bullous Pemphigoid Antigen 1
- Hemidesmosomal Plaque Protein
- 230 240 kDa Bullous Pemphigoid Antigen
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Carrier Proteins (1995-2016)
- Cytoskeletal Proteins (1995-2016)
- Nerve Tissue Proteins (1995-2016)
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AMA Style
References
- National Library of Medicine. Dystonin. Medical Subject Headings (MeSH). 2026. Unique ID D000071821. http://id.nlm.nih.gov/mesh/2026/D000071821
- Dystonin. In: Wikidata. https://www.wikidata.org/wiki/Q21173306