Structured Summary
Abstract
A family of BASIC HELIX-LOOP-HELIX PROTEINS that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.
MeSH Record
Classification
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
7 entry terms
- E2F Proteins
- E2F Transcription Factor
- Transcription Factor E2F
- E2F, Transcription Factor
- Factor, E2F Transcription
- Transcription Factor, E2F
- Transcription Factors, E2F
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1991)
MeSH Record
Previous Indexing
- Cell Cycle Proteins (1991-2005)
- DNA-Binding Proteins (1991-2005)
- Transcription Factors (1991-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. E2F Transcription Factors. Medical Subject Headings (MeSH). 2026. Unique ID D050684. http://id.nlm.nih.gov/mesh/2026/D050684
- E2F Transcription Factors. In: Wikipedia. https://en.wikipedia.org/wiki/E2F
- E2F Transcription Factors. In: Wikidata. https://www.wikidata.org/wiki/Q24771933