Structured Summary
Abstract
An RRM protein that binds to the 3'-UTR region of mRNAs and increases their stability. In EMBRYONIC STEM CELLS, it binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs and preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), to stabilize them and promote differentiation.
MeSH Record
Classification
Broader headings
Related Concepts
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Synonyms
8 entry terms
- ELAVL1 protein
- HuR Antigen
- HuR Paraneoplastic Encephalomyelitis Antigen
- HuR Protein
- Antigen, HuR
- ELAV Like Protein 1
- Protein, HuR
- protein, ELAVL1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2016; use ELAV PROTEINS 2012-2015
MeSH Record
Previous Indexing
- ELAV Proteins (2005-2015)
- RNA-Binding Proteins (2000-2015)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. ELAV-Like Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D000067780. http://id.nlm.nih.gov/mesh/2026/D000067780
- ELAV-Like Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q21113266