Structured Summary
Abstract
One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
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Synonyms
9 entry terms
- Ether-A-Go-Go-Related Potassium Channel 1
- Potassium Voltage-Gated Channel, Subfamily H, Member 2
- Channel, ERG1 Potassium
- Ether A Go Go Related Potassium Channel 1
- Potassium Channel, ERG1
- Kv11.1 Protein-Potassium Channel
- Channel, Kv11.1 Protein-Potassium
- Kv11.1 Protein Potassium Channel
- Protein-Potassium Channel, Kv11.1
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (2001)
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AMA Style
References
- National Library of Medicine. ERG1 Potassium Channel. Medical Subject Headings (MeSH). 2026. Unique ID D000072237. http://id.nlm.nih.gov/mesh/2026/D000072237
- ERG1 Potassium Channel. In: Wikipedia. https://en.wikipedia.org/wiki/KCNH2
- ERG1 Potassium Channel. In: Wikidata. https://www.wikidata.org/wiki/Q905000