Structured Summary
Abstract
Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.
MeSH Record
Classification
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- Echinocandin
- Aculeacin
- Aculeacins
- Mulundocandins
- Pneumocandin
- Pneumocandins
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2008
MeSH Record
Previous Indexing
- Peptides, Cyclic (1981-2007)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Echinocandins. Medical Subject Headings (MeSH). 2026. Unique ID D054714. http://id.nlm.nih.gov/mesh/2026/D054714
- Echinocandins. In: Wikipedia. https://en.wikipedia.org/wiki/Echinocandin
- Echinocandins. In: Wikidata. https://www.wikidata.org/wiki/Q3718510