Chemicals and Drugs

Encainide

One of the ANTI-ARRHYTHMIA AGENTS, it blocks VOLTAGE-GATED SODIUM CHANNELS and slows conduction within the His-Purkinje system and MYOCARDIUM.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

One of the ANTI-ARRHYTHMIA AGENTS, it blocks VOLTAGE-GATED SODIUM CHANNELS and slows conduction within the His-Purkinje system and MYOCARDIUM.

Chemical Identity

Chemical Information

Molecular Formula
C22H28N2O2
Molecular Weight
352.5 g/mol
CAS Registry No.
66778-36-7
IUPAC Name
4-methoxy-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide
InChIKey
PJWPNDMDCLXCOM-UHFFFAOYSA-N
SMILES
CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC
MeSH Unique ID
D016700
Source
PubChem CID 48041

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Encainide Hydrochloride
  • Encainide Hydrochloride, (+-)-Isomer
  • Encainide, (+)-Isomer
  • Encainide, (-)-Isomer
  • Enkaid
  • MJ-9067
  • MJ 9067
  • MJ9067

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

92; was ENCAINIDE (NM) 1979-91

MeSH Record

Previous Indexing

  • Anilides (1966-1991)
  • Anti-Arrhythmia Agents (1966-1991)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Encainide. Medical Subject Headings (MeSH). 2026. Unique ID D016700. http://id.nlm.nih.gov/mesh/2026/D016700
  2. Encainide. In: Wikipedia. https://en.wikipedia.org/wiki/Encainide
  3. Encainide. In: Wikidata. https://www.wikidata.org/wiki/Q514534
  4. Encainide. In: PubChem Compound. CID 48041. https://pubchem.ncbi.nlm.nih.gov/compound/48041