Structured Summary
Abstract
A basic helix-loop-helix transcription factor that regulates expression of genes in response to oxygen, including VASCULAR ENDOTHELIAL GROWTH FACTOR. It plays a role in the development of blood vessels (NEOVASCULARIZATION, PHYSIOLOGIC) and lung tissue.
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Classification
Broader headings
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Synonyms
10 entry terms
- EPAS1 Protein
- Endothelial PAS Protein-1
- HIF-2 alpha
- HIF-Related Factor
- HIF2alpha Protein
- HLF Protein (bHLH-PAS)
- HRF Transcription Factor
- Hypoxia-Inducible Factor 2, alpha Subunit
- Hypoxia-Inducible Factor 2a
- bHLH-PAS Factor HLF
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2026 (1997)
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AMA Style
References
- National Library of Medicine. Endothelial PAS Domain-Containing Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D000099162. http://id.nlm.nih.gov/mesh/2026/D000099162
- Endothelial PAS Domain-Containing Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q21105431