Phenomena and Processes

Endotoxin Tolerance

Reduced capacity to respond to subsequent ENDOTOXIN challenges after an initial exposure. It is characterized by reduced responsiveness of INNATE IMMUNE RESPONSES, a shift from pro- to anti-inflammatory cell phenotype and impaired ANTIGEN PRESENTATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Reduced capacity to respond to subsequent ENDOTOXIN challenges after an initial exposure. It is characterized by reduced responsiveness of INNATE IMMUNE RESPONSES, a shift from pro- to anti-inflammatory cell phenotype and impaired ANTIGEN PRESENTATION.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Endotoxin Desensitization
  • Desensitization, Endotoxin
  • Tolerance, Endotoxin

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2022

MeSH Record

Previous Indexing

  • Endotoxins (1963-2021)
  • Immune Tolerance (1963-2021)

MeSH Hierarchy

Tree Number

  1. G12.535w.425w.290

AMA Style

References

  1. National Library of Medicine. Endotoxin Tolerance. Medical Subject Headings (MeSH). 2026. Unique ID D000087523. http://id.nlm.nih.gov/mesh/2026/D000087523
  2. Endotoxin Tolerance. In: Wikidata. https://www.wikidata.org/wiki/Q112040266