Chemicals and Drugs

Ephedrine

A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.

Chemical Identity

Chemical Information

Molecular Formula
C10H15NO
Molecular Weight
165.23 g/mol
CAS Registry No.
299-42-3
IUPAC Name
(1R,2S)-2-(methylamino)-1-phenylpropan-1-ol
InChIKey
KWGRBVOPPLSCSI-WPRPVWTQSA-N
SMILES
C[C@@H]([C@@H](C1=CC=CC=C1)O)NC
MeSH Unique ID
D004809
Source
PubChem CID 9294

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Erythro Isomer of Ephedrine
  • Ephedrine Erythro Isomer
  • Ephedrine Hydrochloride
  • Ephedrine Renaudin
  • Ephedrine Sulfate
  • Sal-Phedrine
  • Hydrochloride, Ephedrine
  • Renaudin, Ephedrine
  • Sal Phedrine
  • SalPhedrine
  • Sulfate, Ephedrine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.100w.624w.302w
  2. D02w.033w.755.624w.302w
  3. D02w.092w.063w.624w.302w
  4. D02w.092w.471.683w.430w

MeSH Record

NLM Classification

QV 129

AMA Style

References

  1. National Library of Medicine. Ephedrine. Medical Subject Headings (MeSH). 2026. Unique ID D004809. http://id.nlm.nih.gov/mesh/2026/D004809
  2. Ephedrine. In: Wikipedia. https://en.wikipedia.org/wiki/Ephedrine
  3. Ephedrine. In: Wikidata. https://www.wikidata.org/wiki/Q219626
  4. Ephedrine. In: PubChem Compound. CID 9294. https://pubchem.ncbi.nlm.nih.gov/compound/9294