Chemicals and Drugs

Epithelial Cell Adhesion Molecule

A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

20 entry terms
  • Antigen, CD326
  • CD326 Protein
  • ESA Antigen
  • Ep-CAM
  • EpCAM
  • Epithelial Specific Antigen
  • GA 733 Tumor-Associated Antigen
  • GA733 Antigen
  • GA733 Tumor-Associated Antigen
  • Tacstd1 Protein
  • Tumor-Associated Antigen GA733
  • Antigen, ESA
  • Antigen, Epithelial Specific
  • Antigen, GA733
  • CD326 Antigen
  • GA 733 Tumor Associated Antigen
  • GA733 Tumor Associated Antigen
  • GA733, Tumor-Associated Antigen
  • Tumor Associated Antigen GA733
  • Tumor-Associated Antigen, GA733

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1989)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.200w.263w
  2. D12.776w.395w.550w.200w.263w
  3. D12.776w.543w.550w.200w.263w
  4. D23.050w.285.357w
  5. D23.050w.301.350w.263w

AMA Style

References

  1. National Library of Medicine. Epithelial Cell Adhesion Molecule. Medical Subject Headings (MeSH). 2026. Unique ID D000071858. http://id.nlm.nih.gov/mesh/2026/D000071858
  2. Epithelial Cell Adhesion Molecule. In: Wikipedia. https://en.wikipedia.org/wiki/Epithelial_cell_adhesion_molecule
  3. Epithelial Cell Adhesion Molecule. In: Wikidata. https://www.wikidata.org/wiki/Q5383694