Chemicals and Drugs

Ergotamine

A vasoconstrictor found in ergot of Central Europe. It is a serotonin agonist that has been used as an oxytocic agent and in the treatment of MIGRAINE DISORDERS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A vasoconstrictor found in ergot of Central Europe. It is a serotonin agonist that has been used as an oxytocic agent and in the treatment of MIGRAINE DISORDERS.

Chemical Identity

Chemical Information

Molecular Formula
C33H35N5O5
Molecular Weight
581.7 g/mol
CAS Registry No.
113-15-5
IUPAC Name
(6aR,9R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
InChIKey
XCGSFFUVFURLIX-VFGNJEKYSA-N
SMILES
C[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@H]5CN([C@@H]6CC7=CNC8=CC=CC(=C78)C6=C5)C
MeSH Unique ID
D004878
Source
PubChem CID 8223

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Cornutamine
  • Ergo Sanol
  • Ergo-Kranit
  • Ergodryl Mono
  • Ergomar
  • Ergostat
  • Ergotamine Tartrate
  • Ergotamine Tartrate (2:1)
  • Ergotaminine
  • Gynergen
  • Lingraine
  • Ergo Kranit
  • Mono, Ergodryl
  • Tartrate, Ergotamine

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

ERGOTAMINE TARTRATE was ERGOTAMINE TARTRATE (NM) 1975-91

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Ergotamine. Medical Subject Headings (MeSH). 2026. Unique ID D004878. http://id.nlm.nih.gov/mesh/2026/D004878
  2. Ergotamine. In: Wikipedia. https://en.wikipedia.org/wiki/Ergotamine
  3. Ergotamine. In: Wikidata. https://www.wikidata.org/wiki/Q419186
  4. Ergotamine. In: PubChem Compound. CID 8223. https://pubchem.ncbi.nlm.nih.gov/compound/8223