Chemicals and Drugs

Ethinyl Estradiol

A semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES.

Chemical Identity

Chemical Information

Molecular Formula
C20H24O2
Molecular Weight
296.4 g/mol
CAS Registry No.
57-63-6
IUPAC Name
(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
InChIKey
BFPYWIDHMRZLRN-SLHNCBLASA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O
MeSH Unique ID
D004997
Source
PubChem CID 5991

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

20 entry terms
  • 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-
  • Ethinyloestradiol
  • Ethynyl Estradiol
  • Estradiol, Ethinyl
  • Estradiol, Ethynyl
  • Estinyl
  • Ethinyl Estradiol Hemihydrate
  • Ethinyl Estradiol, (8 alpha)-Isomer
  • Ethinyl Estradiol, (8 alpha,17 alpha)-Isomer
  • Ethinyl Estradiol, (8 alpha,9 beta,13 alpha,14 beta)-Isomer
  • Ethinyl Estradiol, (9 beta,17 alpha)-Isomer
  • Ethinyl-Oestradiol Effik
  • Ethinylestradiol Jenapharm
  • Lynoral
  • Microfollin
  • Microfollin Forte
  • Progynon C
  • Ethinyl Oestradiol Effik
  • Hemihydrate, Ethinyl Estradiol
  • Jenapharm, Ethinylestradiol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.668w.651.568.291w
  2. D06.472w.334.851w.437.968.500w

AMA Style

References

  1. National Library of Medicine. Ethinyl Estradiol. Medical Subject Headings (MeSH). 2026. Unique ID D004997. http://id.nlm.nih.gov/mesh/2026/D004997
  2. Ethinyl Estradiol. In: Wikipedia. https://en.wikipedia.org/wiki/Ethinylestradiol
  3. Ethinyl Estradiol. In: Wikidata. https://www.wikidata.org/wiki/Q415563
  4. Ethinyl Estradiol. In: PubChem Compound. CID 5991. https://pubchem.ncbi.nlm.nih.gov/compound/5991