Chemicals and Drugs

Ethyl Methanesulfonate

An antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect.

Chemical Identity

Chemical Information

Molecular Formula
C3H8O3S
Molecular Weight
124.16 g/mol
CAS Registry No.
62-50-0
IUPAC Name
ethyl methanesulfonate
InChIKey
PLUBXMRUUVWRLT-UHFFFAOYSA-N
SMILES
CCOS(=O)(=O)C
MeSH Unique ID
D005020
Source
PubChem CID 6113

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Ethyl Mesilate
  • Ethyl Mesylate
  • Ethylmesilate
  • Ethylmesylate
  • Ethylmethane Sulfonate
  • Mesilate, Ethyl
  • Mesylate, Ethyl
  • Methanesulfonate, Ethyl
  • Sulfonate, Ethylmethane

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

80(75); was see under METHANESULFONATES 1975-79; ETHYLMESYLATE & MESILATE, ETHYL were see ETHYL METHANESULFONATE 1981-93; ETHYL MESILATE was see ETHYL METHANESULFONATE 1980-93

MeSH Record

Previous Indexing

  • Alkanes (1966-1973)
  • Methane (1966-1973)
  • Methanesulfonates (1974)
  • Sulfonic Acids (1966-1973)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.326.146w.100.050.500w.300w
  2. D02w.886w.645.600w.055.050.510w.300w

AMA Style

References

  1. National Library of Medicine. Ethyl Methanesulfonate. Medical Subject Headings (MeSH). 2026. Unique ID D005020. http://id.nlm.nih.gov/mesh/2026/D005020
  2. Ethyl Methanesulfonate. In: Wikipedia. https://en.wikipedia.org/wiki/Ethyl_methanesulfonate
  3. Ethyl Methanesulfonate. In: Wikidata. https://www.wikidata.org/wiki/Q416643
  4. Ethyl Methanesulfonate. In: PubChem Compound. CID 6113. https://pubchem.ncbi.nlm.nih.gov/compound/6113