Chemicals and Drugs

Factor IXa

Activated form of factor IX. This activation can take place via the intrinsic pathway of blood coagulation by the action of factor XIa and calcium, or via the extrinsic pathway by the action of factor VIIa, thromboplastin, and calcium. Factor IXa serves to activate factor X to Xa by cleaving the arginyl-leucine peptide bond in factor X.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Activated form of factor IX. This activation can take place via the intrinsic pathway of blood coagulation by the action of factor XIa and calcium, or via the extrinsic pathway by the action of factor VIIa, thromboplastin, and calcium. Factor IXa serves to activate factor X to Xa by cleaving the arginyl-leucine peptide bond in factor X.

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Classification

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Synonyms

7 entry terms
  • Blood Coagulation Factor IX, Activated
  • Coagulation Factor IXa
  • Factor 9A
  • Factor IX, Activated
  • Factor Nine A
  • Activated Factor IX
  • Factor IXa, Coagulation

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Factor IX (1975-1989)
  • Serine Proteinases (1988-1989)

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AMA Style

References

  1. National Library of Medicine. Factor IXa. Medical Subject Headings (MeSH). 2026. Unique ID D015949. http://id.nlm.nih.gov/mesh/2026/D015949
  2. Factor IXa. In: Wikidata. https://www.wikidata.org/wiki/Q50259256