Chemicals and Drugs

Fadrozole

A selective aromatase inhibitor effective in the treatment of estrogen-dependent disease including breast cancer.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A selective aromatase inhibitor effective in the treatment of estrogen-dependent disease including breast cancer.

Chemical Identity

Chemical Information

Molecular Formula
C14H13N3
Molecular Weight
223.27 g/mol
CAS Registry No.
102676-47-1
IUPAC Name
4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile
InChIKey
CLPFFLWZZBQMAO-UHFFFAOYSA-N
SMILES
C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N
MeSH Unique ID
D017316
Source
PubChem CID 59693

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • CGS 020286A
  • CGS-020286A
  • CGS-16949A
  • CGS020286A
  • FAD 286
  • FAD-286
  • FAD286
  • Fadrozole Hydrochloride
  • Fadrozole Monohydrochloride
  • CGS 16949A
  • CGS16949A
  • Hydrochloride, Fadrozole
  • Monohydrochloride, Fadrozole

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1993

MeSH Record

Previous Indexing

  • Imidazoles (1988-1992)
  • Nitriles (1988-1992)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Fadrozole. Medical Subject Headings (MeSH). 2026. Unique ID D017316. http://id.nlm.nih.gov/mesh/2026/D017316
  2. Fadrozole. In: Wikipedia. https://en.wikipedia.org/wiki/Fadrozole
  3. Fadrozole. In: Wikidata. https://www.wikidata.org/wiki/Q5429279
  4. Fadrozole. In: PubChem Compound. CID 59693. https://pubchem.ncbi.nlm.nih.gov/compound/59693