Chemicals and Drugs

Fanconi Anemia Complementation Group D2 Protein

A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • FANCD2 Protein
  • Fanconi Anemia Group D2 Complementing Protein
  • Fanconi Anemia Group D2 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(2001)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.313.812
  2. D12.776w.660w.285
  3. D12.776w.744w.484

AMA Style

References

  1. National Library of Medicine. Fanconi Anemia Complementation Group D2 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D052236. http://id.nlm.nih.gov/mesh/2026/D052236
  2. Fanconi Anemia Complementation Group D2 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21100488