Chemicals and Drugs

Febuxostat

A thiazole derivative and inhibitor of XANTHINE OXIDASE that is used for the treatment of HYPERURICEMIA in patients with chronic GOUT.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thiazole derivative and inhibitor of XANTHINE OXIDASE that is used for the treatment of HYPERURICEMIA in patients with chronic GOUT.

Chemical Identity

Chemical Information

Molecular Formula
C16H16N2O3S
Molecular Weight
316.4 g/mol
CAS Registry No.
144060-53-7
IUPAC Name
2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
InChIKey
BQSJTQLCZDPROO-UHFFFAOYSA-N
SMILES
CC1=C(SC(=N1)C2=CC(=C(C=C2)OCC(C)C)C#N)C(=O)O
MeSH Unique ID
D000069465
Source
PubChem CID 134018

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid
  • TEI 6720
  • TEI-6720
  • Uloric
  • 6720, TEI
  • TEI6720

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1994)

MeSH Hierarchy

Tree Numbers

  1. D02w.886w.675.274w
  2. D03w.383.129w.708.274w

AMA Style

References

  1. National Library of Medicine. Febuxostat. Medical Subject Headings (MeSH). 2026. Unique ID D000069465. http://id.nlm.nih.gov/mesh/2026/D000069465
  2. Febuxostat. In: Wikipedia. https://en.wikipedia.org/wiki/Febuxostat
  3. Febuxostat. In: Wikidata. https://www.wikidata.org/wiki/Q417296
  4. Febuxostat. In: PubChem Compound. CID 134018. https://pubchem.ncbi.nlm.nih.gov/compound/134018