Chemicals and Drugs

Felbamate

A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A PEGylated phenylcarbamate derivative that acts as an antagonist of NMDA RECEPTORS. It is used as an anticonvulsant, primarily for the treatment of SEIZURES in severe refractory EPILEPSY.

Chemical Identity

Chemical Information

Molecular Formula
C11H14N2O4
Molecular Weight
238.24 g/mol
CAS Registry No.
25451-15-4
IUPAC Name
(3-carbamoyloxy-2-phenylpropyl) carbamate
InChIKey
WKGXYQFOCVYPAC-UHFFFAOYSA-N
SMILES
C1=CC=C(C=C1)C(COC(=O)N)COC(=O)N
MeSH Unique ID
D000078328
Source
PubChem CID 3331

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • 2-Phenyl-1,3-propanediol dicarbamate
  • 2 Phenyl 1,3 propanediol dicarbamate
  • (3-Carbamoyloxy-2-phenyl-propyl) carbamate
  • ADD-03055
  • Felbamyl
  • Felbatol
  • Taloxa
  • W-554
  • ADD 03055
  • ADD03055
  • W 554
  • W554

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1986)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Felbamate. Medical Subject Headings (MeSH). 2026. Unique ID D000078328. http://id.nlm.nih.gov/mesh/2026/D000078328
  2. Felbamate. In: Wikipedia. https://en.wikipedia.org/wiki/Felbamate
  3. Felbamate. In: Wikidata. https://www.wikidata.org/wiki/Q421301
  4. Felbamate. In: PubChem Compound. CID 3331. https://pubchem.ncbi.nlm.nih.gov/compound/3331