Structured Summary
Abstract
A family of extracellular matrix glycoproteins that is structurally similar to LATENT TGF-BETA BINDING PROTEINS, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm MICROFIBRILS that function in a variety of cell interactions with the EXTRACELLULAR MATRIX and developmental processes such as ELASTIC TISSUE maintenance and assembly, and the targeting of growth factors to the extracellular matrix.
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1 entry terms
- Fibrillin
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2017; use FIBRILLIN 1985-2016
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References
- National Library of Medicine. Fibrillins. Medical Subject Headings (MeSH). 2026. Unique ID D000071837. http://id.nlm.nih.gov/mesh/2026/D000071837
- Fibrillins. In: Wikipedia. https://en.wikipedia.org/wiki/Fibrillin
- Fibrillins. In: Wikidata. https://www.wikidata.org/wiki/Q2909678