Chemicals and Drugs

Fibrinolysin

A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Glu-Plasmin
  • Plasmin
  • Protease F
  • Glu Plasmin
  • Fibrogammin
  • Thrombolysin

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010, 1963-1992;

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Fibrinolysin. Medical Subject Headings (MeSH). 2026. Unique ID D005341. http://id.nlm.nih.gov/mesh/2026/D005341
  2. Fibrinolysin. In: Wikipedia. https://en.wikipedia.org/wiki/Fibrinolysin
  3. Fibrinolysin. In: Wikidata. https://www.wikidata.org/wiki/Q2619971