Structured Summary
Abstract
S100 proteins that aggregate KERATINS. Filaggrin precursor proteins are localized in keratohyalin granules and processed into individual functional filaggrin molecules during terminal epidermis differentiation. Mutations in fillagrins are associated with ICHTHYOSIS VULGARIS.
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Synonyms
7 entry terms
- Filaggrin
- Filaggrin Protein
- Stratum Corneum Basic Protein
- Protein, Filaggrin
- Proteins, Filaggrin
- Profilaggrin
- Stratum Corneum Basic Protein Precursor
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2022(1981)
MeSH Record
Previous Indexing
- Intermediate Filament Proteins (1982-2021)
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References
- National Library of Medicine. Filaggrin Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D000091344. http://id.nlm.nih.gov/mesh/2026/D000091344
- Filaggrin Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q24778881