Chemicals and Drugs

Flunitrazepam

A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.

Chemical Identity

Chemical Information

Molecular Formula
C16H12FN3O3
Molecular Weight
313.28 g/mol
CAS Registry No.
1622-62-4
IUPAC Name
5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
InChIKey
PPTYJKAXVCCBDU-UHFFFAOYSA-N
SMILES
CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F
MeSH Unique ID
D005445
Source
PubChem CID 3380

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

18 entry terms
  • Fluridrazepam
  • Fluni 1A Pharma
  • Flunibeta
  • Flunimerck
  • Fluninoc
  • Flunitrazepam-Neuraxpharm
  • Flunitrazepam-Ratiopharm
  • Flunitrazepam-Teva
  • Flunizep Von Ct
  • Narcozep
  • RO-5-4200
  • Rohipnol
  • Rohypnol
  • Flunitrazepam Neuraxpharm
  • Flunitrazepam Ratiopharm
  • Flunitrazepam Teva
  • RO54200
  • Von Ct, Flunizep

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

colloquially called "rophies" and "roofies" from entry term ROHYPNOL

MeSH Record

History Note

84(75); was see under BENZODIAZEPINE TRANQUILIZERS 1975-83

MeSH Record

Previous Indexing

  • Benzodiazepinones (1974)
  • Fluorobenzenes (1974)
  • Nitro Compounds (1974)

MeSH Hierarchy

Tree Number

  1. D03w.633.100.079.080w.070.320w

AMA Style

References

  1. National Library of Medicine. Flunitrazepam. Medical Subject Headings (MeSH). 2026. Unique ID D005445. http://id.nlm.nih.gov/mesh/2026/D005445
  2. Flunitrazepam. In: Wikipedia. https://en.wikipedia.org/wiki/Flunitrazepam
  3. Flunitrazepam. In: Wikidata. https://www.wikidata.org/wiki/Q62947
  4. Flunitrazepam. In: PubChem Compound. CID 3380. https://pubchem.ncbi.nlm.nih.gov/compound/3380